| Sunday, November 22, 2009 | Game/2ndH | 1stH | 1stQ | 2ndQ | 3rdQ | 4thQ |
| # | Team Name | Spread | Total | MoneyLn | T1 Total | T2 Total |
| 1:00 pm |
| 407 | Cleveland Browns | -115 | +160 | 17½ +105 | +110 | |
| 408 | Detroit Lions | -3½ -105 | 38 | -185 | -135 | 21½ -140 |
| 1:00 pm |
| 409 | Buffalo Bills | -125 | +330 | 17 -110 | -110 | |
| 410 | Jacksonville Jaguars | -9 +105 | 42½ | -420 | -120 | 26 -120 |
| 1:00 pm |
| 411 | Pittsburgh Steelers | -10 -105 | 40½ | -475 | 24½ -120 | -120 |
| 412 | Kansas City Chiefs | -115 | +375 | -110 | 14½ -110 |
| 1:00 pm |
| 413 | IndianapoIis Colts | -1 -115 | 44½ | -120 | 22½ -130 | +115 |
| 414 | Baltimore Ravens | -105 | +100 | +100 | 22½ -145 |
| 1:00 pm |
| 415 | Atlanta Falcons | -120 | +260 | 20 -115 | -115 | |
| 416 | New York Giants | -7 +100 | 46 | -320 | -115 | 26 -115 |
| 1:00 pm |
| 417 | San Francisco 49ers | +240 | 17½ +100 | +105 | ||
| 418 | Green Bay Packers | -6½ | 42 | -280 | -130 | 24½ -135 |
| 1:00 pm |
| 419 | Seattle Seahawks | +425 | 17 -120 | +105 | ||
| 420 | Minnesota Vikings | -10½ | 46 | -550 | -110 | 30 -135 |
| 1:00 pm |
| 421 | Washington Redskins | +450 | 14½ -120 | -115 | ||
| 422 | Dallas Cowboys | -11 | 41½ | -600 | -110 | 26½ -115 |
| 1:00 pm |
| 423 | New Orleans Saints | -11 -105 | 50½ | -550 | 31 -115 | -115 |
| 424 | Tampa Bay Buccaneers | -115 | +425 | -115 | 20 -115 |
| 4:05 pm |
| 425 | Arizona Cardinals | -9 +100 | 46½ | -400 | 28 -115 | -115 |
| 426 | St Louis Rams | -120 | +320 | -115 | 19 -115 |
| 4:15 pm |
| 427 | New York Jets | +475 | 17 -115 | -115 | ||
| 428 | New England Patriots | -10½ | 45 | -650 | -115 | 27½ -115 |
| 4:15 pm |
| 429 | Cincinnati Bengals | -9 -105 | 36 | -450 | 22½ -130 | -115 |
| 430 | Oakland Raiders | -115 | +350 | +100 | 13½ -115 |
| 8:20 pm (NBC) |
| 433 | Philadelphia Eagles | -3 | 44½ | -160 | 23½ -115 | -115 |
| 434 | Chicago Bears | +140 | -115 | 21 -115 |
| Monday, November 23, 2009 | Game/2ndH | 1stH | 1stQ | 2ndQ | 3rdQ | 4thQ |
| # | Team Name | Spread | Total | MoneyLn | T1 Total | T2 Total |
| 8:35 pm (ESPN) |
| 435 | Tennessee Titans | -115 | +180 | 21½ -120 | -115 | |
| 436 | Houston Texans | -4½ -105 | 48 | -220 | -110 | 26½ -115 |
| Line Changes Made Within Last 15 Minutes Are | Highlighted. |